Parentage = H. argutifolius × H. niger

Active principles: aerial parts: cardiac glycosides (bufadienolides), hellebrin, steroid saponins (helleborin), ranunculoside, alkaloids (celliamine, sprintillamine).

Wink, M. (2009). Mode of Action and toxicology of plant toxins and poisonous plants. Mitt. Julius Kuhn-Inst. 421:93-111. p.99

Class 1a: Extremely hazardous: cardiac glycosides inhibit Na+,K+-ATPase, cardiac glycoside intoxication, vomiting, gastroenteritis with violent diarrhoea, delirium, convulsions, arrhythmia, death by respiratory arrest, alkaloids have similar properties as veratrine and aconitine.

Wink, M. (2009). Mode of Action and toxicology of plant toxins and poisonous plants. Mitt. Julius Kuhn-Inst. 421:93-111. p.99