Class 1b, Highly hazardous; cardiac glycosides inhibit Na+,K+-ATPase, irritation of GI tract, nausea, hallucinations, extensive vomiting, shock, hyperthermia, bloody diarrhoea, liver and kidney disturbance, arrhythmia, strong spasms, coma after 12 h, cardiac arrest.

Wink, M. (2009). Mode of Action and toxicology of plant toxins and poisonous plants. Mitt. Julius Kuhn-Inst. 421:93-111. p.99

Toxic due to content of cardio-active cardenolides.

Professor Anthony Dayan, 2022

Active principle: (for Euonymus europaea and related species): all parts, especially fruits: evobioside, evomonoside and other cardenolides, evonine and several alkaloids.

Wink, M. (2009). Mode of Action and toxicology of plant toxins and poisonous plants. Mitt. Julius Kuhn-Inst. 421:93-111. p.99