Used in traditional medicine since the 3rd century BC

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An antiviral drug based on a traditional Mediterranean remedy is showing promising results against COVID-19 infection, scientists have reported.

Al-Beltagi S, Preda C, Goulding L et al. https://doi.org/10.3390/v13020234

Highly irritant to skin on contact and to airways if inhaled. Contains Thapsigargin a tryclic diterpene that inhibits ATPases, notably in the endoplasmic reticulum, and calcium entry into cells. It is a novel TRPV1 inhibitor. Being studied as an anticancer and antiviral drug. Clinically in cattle causes nervousness, twitching, convulsions and death

João B. Calixto, Candida A.L. Kassuya, Eunice André, Juliano Ferreira 2005. Contribution of natural products to the discovery of the transient receptor potential (TRP) channels family and their functions, Pharmacol Ther, 106, 179.

Europe, Southwestern Europe, France

Europe, Southwestern Europe, Portugal

Europe, Southwestern Europe, Spain